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ReVia slide 5 of 5, ReVia,. What is the most important information I should know about naltrexone? What is naltrexone? Naltrexone is not a cure for drug addiction or alcoholism. Naltrexone may also be used for purposes not listed in this medication guide. What should I discuss with my health care provider before taking naltrexone? You should not use naltrexone if you are allergic to it, or if:.
Naltrexone is not approved for use by anyone younger than 18 years old. How should I use naltrexone? Take the naltrexone tablet with a full glass of water. Naltrexone may be taken with food if it upsets your stomach. What happens if I miss a dose?
What happens if I overdose? What should I avoid while using naltrexone? Do not drink alcohol while you are taking naltrexone. What are the possible side effects of naltrexone? What other drugs will affect naltrexone?
Where can I get more information? Your pharmacist can provide more information about naltrexone. Copyright Cerner Multum, Inc. Version: 4. Consider keeping a card in your wallet stating you are taking naltrexone to alert caregivers in case of emergency. While on naltrexone, opioid pain medicines will not work. Other types of pain medications such as ibuprofen, naproxen, or acetaminophen are not affected.
If you are planning on becoming pregnant, notify your healthcare provider to best manage your medications. People living with substance use disorders that wish to become pregnant face important decisions and challenges. Active substance use disorders during pregnancy put the fetus at great risk. It is important to discuss the risks and benefits of continued treatment with your doctor and caregivers. The effects of naltrexone on the fetus when used in pregnant women are unknown.
It is likely that naltrexone crosses the placenta and can be transferred to the fetus. Naltrexone did not appear to cause structural abnormalities during animal studies; however, there appeared to be some behavioral alterations as well as early fetal loss.
These results cannot be applied to humans; therefore, naltrexone should only be used in pregnancy if the benefits outweigh the risk to the fetus. Breastfeeding while taking naltrexone is not recommended, as it is likely that naltrexone crosses into the breast milk.
The effects of naltrexone on the baby are unknown. Naltrexone is available as an oral tablet and an intramuscular injection. Only your healthcare provider can determine the route of administration and correct dose for you. Naltrexone oral tablets are usually taken once daily with or without food. Taking naltrexone tablets with food may decrease stomach upset. Typically, people are given a test dose of 25 mg daily to ensure they can tolerate the medication. If the low dose is tolerated, the dose is increased to 50 mg daily.
The injection dose is mg given intramuscularly every four weeks. These injections are given by your doctor, nurse, or pharmacist. Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or a friend to remind you or check in with you to be sure you are taking your medication.
If you miss a dose of oral naltrexone, take it as soon as you remember unless it is closer to the time of your next dose. Do not double your next dose or take more than what is prescribed. Avoid drinking alcohol, using opioid pain medications such as codeine, hydrocodone, oxycodone, or morphine , or using illegal drugs while you are taking naltrexone. They may increase adverse effects e. Keep in mind that some cough syrups may contain opioid pain medication. Discuss all medications with your doctor and pharmacist prior to taking naltrexone.
If an overdose occurs, call your doctor or You may need urgent medical care. You may also contact the poison control center at You should always call after giving someone naloxone to treat an overdose. Ask your provider if prescription naloxone is right for you or your family member to have available.
To date, there are no known problems associated with long term use of naltrexone. It is a safe and effective medication when used as directed. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. It is very important that your doctor check your progress at regular visits. Your doctor may want to do certain blood tests to see if the medicine is causing unwanted effects. This medicine blocks the "high" feeling you get from narcotic opioid drugs, including heroin. Since naltrexone may make you more sensitive to lower doses of opioids than you have previously used, you should not use heroin or any other narcotic drugs to overcome what the medicine is doing.
You could overdose and develop serious problems. This medicine may cause serious problems with your liver. Call your doctor right away if you start having dark urine, pain in the upper stomach, or yellowing of the eyes or skin while you are using this medicine.
This medicine may increase thoughts of suicide. Tell your doctor right away if you start to feel more depressed. Also tell your doctor right away if you have thoughts about hurting yourself. Report any unusual thoughts or behaviors that trouble you, especially if they are new or get worse quickly.
Make sure your caregiver knows if you feel tired all the time, sleep a lot more or a lot less than usual, feel hopeless or helpless, or if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless.
Also tell your doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Remember that use of naltrexone is only part of your treatment. Do not try to overcome the effects of naltrexone by taking narcotics. To do so may cause coma or death. You may be more sensitive to the effects of narcotics than you were before beginning naltrexone therapy.
Naltrexone also blocks the useful effects of narcotics. Always use a non-narcotic medicine to treat pain, diarrhea, or a cough. If you have any questions about the proper medicine to use, check with your doctor. Naltrexone will not prevent you from becoming impaired when you drink alcohol. Do not take naltrexone in order to drive or perform other activities while under the influence of alcohol.
This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. If any of these side effects occur, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert while you are taking naltrexone. Never share this medicine with anyone else, especially someone who is using narcotics.
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